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$1,248,000
1 Day On Site

643 Grand Avenue
South San Francisco, CA 94080

For Sale|Single Family Residence|Active
3
Beds
4
Total Baths
4
Full Baths
1,630
SqFt
$766
/SqFt
1895
Built
County:
San Mateo
Listed by Jill Penna of Christie's International Real Estate Sereno [email protected]
Upcoming Open Houses
Sat, Aug 29, 1:00 PM - 4:00 PM
Sun, Aug 30, 1:00 PM - 4:00 PM
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Mortgage Calculator

Monthly Payment (Est.)

$5,694
Calculator powered by Showcase IDX, a Constellation1 Company. Copyright ©2026 Information is deemed reliable but not guaranteed.

Ideally located near Downtown South San Francisco and the cities thriving biotech and life-sciences corridor, 643 Grand Avenue where space, comfort, and a remarkable garden setting come together in the heart of South San Francisco. 643 Grand Avenue offers a spacious and versatile layout with excellent access to major transportation and employment centers. The home features 3 bedrooms and 4 bathrooms, with a private full bathroom for each bedroom. Additional highlights include high ceilings, abundant natural light, hardwood floors, a full basement with ample storage, and a detached 2-car garage equipped with a 220-volt outlet for EV charging. The home also features a water purification system, tankless water heater, and water softener. The quaint lot includes a freshly manicured organic vegetable garden with sunflowers and offers potential for an ADU. Conveniently located near Downtown South San Francisco, Genentech, Caltrain, US-101, and I-280.

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Listing Snapshot
Price 
$1,248,000
Days On Site 
1 Day
Bedrooms 
3
Inside Area (SqFt) 
1,630 sqft
Total Baths 
4
Full Baths 
4
Partial Baths 
N/A
Lot Size 
0.0803 Acres
Year Built 
1895
MLS® Number 
ML82059314
Status 
Active
Property Tax 
N/A
HOA/Condo/Coop Fees 
N/A
Sq Ft Source 
Assessor
Friends & Family
Recent Activity
yesterdayListing updated with changes from the MLS®
yesterdayListing first seen on site
General Features
Acres 
0.0803
Foundation 
Slab
Garage 
Yes
Garage Spaces 
2
Number Of Stories 
2
Parking Spaces 
2
Property Sub Type 
Single Family Residence
Sewer 
Public Sewer
Special Circumstances 
Standard
Water Source 
Public
Zoning 
RM0000
Interior Features
Cooling 
None
Heating 
Central
Window Features 
Skylight(s)
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Exterior Features
Roof 
Shingle
Windows/Doors 
Skylight(s)
Community Features
MLS Area 
699 - Not Defined
School District 
South San Francisco Unified
Schools
School District
South San Francisco Unified
Elementary School
Unknown
Middle School
Unknown
High School
Unknown


This information is for your personal, non-commercial use and may not be used for any purpose other than to identify prospective properties you may be interested in purchasing. The display of MLS data is usually deemed reliable but is NOT guaranteed accurate by the MLS. Buyers are responsible for verifying the accuracy of all information and should investigate the data themselves or retain appropriate professionals. Information from sources other than the Listing Agent may have been included in the MLS data. Unless otherwise specified in writing, the Broker/Agent has not and will not verify any information obtained from other sources. The Broker/Agent providing the information contained herein may or may not have been the Listing and/or Selling Agent.

Neighborhood & Commute
Source: Walkscore
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